Article
Genetic characterization of acquired aplastic anemia by targeted sequencing
6 Jun 2014
Abstract excerpt
Aplastic anemia (AA) is a rare but life-threatening bone marrow failure syndrome; diagnosis is based on cytopenias in peripheral blood and hypocellularity in bone marrow. The distinction between AA and hypocellular myelodysplastic syndrome (MDS) is often difficult to verify, and AA evolves into MDS or AML at a 10-year cumulative incidence of 3.1-9.6%. As AA patients often respond to immunosuppressive therapy, an...
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