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Article

[Somatic Mutations of Acquired Aplastic Anemia].

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 1 Jun 2022

Zhang Meng-Lu, Chen Wan-Shu, Han Bing

Abstract excerpt

Aplastic anemia (AA) and myelodysplastic syndrome (MDS) are clonal diseases with hemopoietic stem cell (HSC) abnormalities,which are sometimes difficult to be distinguished from each other.The development of molecular detection techniques has facilitated our understanding of the molecular pathogenesis of the two diseases.This article reviewed the somatic mutation (SM) and cytogenetic changes of AA,and analyzed...

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PMID: 35791949
DOI: 10.3881/j.issn.1000-503X.13381

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