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Article

Role of RNA Domain Structure and Orientation in the Coxsackievirus B3 Virulence Phenotype.

Journal of virology - 31 May 2023

Phillips Lydia, Tapprich William E

Abstract excerpt

Coxsackievirus B3 (CVB3) is an enterovirus that causes diseases such as pancreatitis and myocarditis in humans. Approximately 10% of the CVB3 RNA genome consists of a highly structured 5' untranslated region (5' UTR) that is organized into six domains and contains a type I internal ribosome entry site (IRES). These features are common to all enteroviruses. Each RNA domain plays a vital role in translation and...

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Identifiers

PMID: 37074194
DOI: 10.1128/jvi.00448-23
PMCID: PMC10231185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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