Article
Revisiting the prognostic role of FLT3 mutations in acute myelogenous leukemia.
Expert review of hematology - 1 May 2023
Reikvam Håkon
Abstract excerpt
INTRODUCTION: Approximately one-third of patients with acute myelogenous leukemia (AML) harbor mutations in the fms-like tyrosine kinase 3 (FLT3) gene. The features regarding prognostic impact of FLT3 mutated AML have been widely investigated and debated in the last decades, and the significance of this mutation is constantly evolving. AREAS COVERED: In this article, the significance of the FLT3 mutation and...
Topics
- Humans
- fms-Like Tyrosine Kinase 3
- Leukemia, Myeloid, Acute
- Mutation
- Prognosis
