Article
FLT3-ITD and its current role in acute myeloid leukaemia.
Medical oncology (Northwood, London, England) - 1 Jun 2017
Lagunas-Rangel Francisco Alejandro, Chávez-Valencia Venice
Abstract excerpt
FMS-like tyrosine kinase 3 (FLT3) is a proto-oncogene involved in crucial steps of haematopoiesis such as proliferation, differentiation and survival. In recent years, FLT3 has been an important marker in different haematological malignancies, highlighting in acute myeloid leukaemia, where FLT3 mutations have been associated with the clinical prognosis, treatment and survival of patients. The most common form of...
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