Article
Potential targeting of FLT3 acute myeloid leukemia.
Haematologica - 1 Mar 2021
Ambinder Alexander J, Levis Mark
Abstract excerpt
Aberrant FLT3 receptor signaling is common in acute myeloid leukemia (AML) and has important implications for the biology and clinical management of the disease. Patients with FLT3-mutated AML frequently present with critical illness, are more likely to relapse after treatment, and have worse cli...
Topics
- Humans
- Leukemia, Myeloid, Acute
- Mutation
- Neoplasm, Residual
- Protein Kinase Inhibitors
- Recurrence
- fms-Like Tyrosine Kinase 3