Article
Fms -like tyrosine kinase 3 positive acute myeloid leukemia.
Current opinion in oncology - 1 Nov 2023
Isidori Alessandro, Visani Giuseppe, Ferrara Felicetto
Abstract excerpt
PURPOSE OF REVIEW: Fms -like tyrosine kinase 3 (FLT3) mutations are common in newly diagnosed patients with acute myeloid leukemia (AML). They are associated with a high risk of relapse. The identification of FLT3 mutations has important implications for the management of AML. FLT3 inhibitors have shown improved outcomes in FLT3-positive AML when used as a single agent in the salvage setting. However, the...
Topics
- Humans
- Antineoplastic Agents
- Protein Kinase Inhibitors
- fms-Like Tyrosine Kinase 3
- Leukemia, Myeloid, Acute
- Prognosis
- Mutation
