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Article

ASXL1 mutations in myeloid neoplasms: pathogenetic considerations, impact on clinical outcomes and survival.

Current medical research and opinion - 1 May 2018

Alvarez Argote Juliana, Dasanu Constantin A

Abstract excerpt

BACKGROUND: ASXL1 gene mutations include nonsense, missense, and frameshift mutations. Although their clinical significance is still debated, they may play an important role in the pathogenesis of several hematologic malignancies. METHODS: Herein, we offer a comprehensive review on ASXL1 mutations, and link them with survival and clinical outcomes in patients with various myeloid neoplasms. Most relevant...

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Source

Identifiers

PMID: 28027687
DOI: 10.1080/03007995.2016.1276896

Genes

ASXL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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