Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bias correction for inverse variance weighting Mendelian randomization.

Genetic epidemiology - 1 Jun 2023

Mounier Ninon, Kutalik Zoltán

Abstract excerpt

Inverse-variance weighted two-sample Mendelian randomization (IVW-MR) is the most widely used approach that utilizes genome-wide association studies (GWAS) summary statistics to infer the existence and the strength of the causal effect between an exposure and an outcome. Estimates from this approach can be subject to different biases due to the use of weak instruments and winner's curse, which can change as a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bias
Share to Genome-Wide Association Study
Share to Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 37036286
DOI: 10.1002/gepi.22522

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bias correction for inverse variance weighting Mendelian randomization.PMID 37036286Read ↗

MRBEE: A novel bias-corrected multivariable Mendelian Randomization methodSemantic proximity Read ↗

Combining the strengths of inverse-variance weighting and Egger regression in Mendelian randomization using a mixture of regressions model.Semantic proximity Read ↗

MRBEE: A bias-corrected multivariable Mendelian randomization method.Semantic proximity Read ↗

A Modified Debiased Inverse-Variance Weighted Estimator in Two-Sample Summary-Data Mendelian Randomization.Semantic proximity Read ↗

Benchmarking Mendelian randomization methods for causal inference using genome-wide association study summary statistics.Semantic proximity Read ↗

A Review of Mendelian Randomization: Assumptions, Methods, and Application to Obesity-Related DiseasesSemantic proximity Read ↗

[Mendelian randomization approach, used for causal inferences].Semantic proximity Read ↗

METEOR: a data-adaptive Mendelian randomization method for powerful detection of shared and specific exposures underlying multiple outcomes.Semantic proximity Read ↗

Dietary Intake Mendelian Randomization: Assessment and Development of Methods for Instrument Selection and Robust InferenceSemantic proximity Read ↗

Mendelian Randomization.Semantic proximity Read ↗

A multivariable cis-Mendelian randomization method robust to weak instrument bias and horizontal pleiotropy bias.Semantic proximity Read ↗

A Guide to Understanding Mendelian Randomization StudiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.