Article
Specific human leukocyte antigen class I genotypes predict prognosis in resected pancreatic adenocarcinoma: a retrospective cohort study.
International journal of surgery (London, England) - 1 Jul 2023
Wen Chenlei, Zhang Lei, Yang Ying, Jin Yangbing, Ren Dandan, Zhang Zehui, Zou Siyi, Li Fanlu, Sun Huaibo, Jin Jiabin, Lu Xiongxiong, Xie Junjie, Cheng Dongfeng, Xu Zhiwei, Chen Huan, Mao Beibei, Zhang Jun, Wang Jiancheng, Deng Xiaxing, Peng Chenghong, Li Hongwei, Jiang Cen, Lin Lin, Zhang Henghui, Chen Hao, Shen Baiyong, Zhan Qian
Abstract excerpt
BACKGROUND: Patients with resected pancreatic adenocarcinoma (PAAD) often experience short-term relapse and dismal survival, suggesting an urgent need to develop predictive and/or prognostic biomarkers for these populations. Given the potential associations of the human leukocyte antigen class I ( HLA -I) genotype with oncogenic mutational profile and immunotherapy efficacy, we aimed to assess whether...
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