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Differential role of HLA-A and HLA-B, C expression levels as prognostic markers in colon and rectal cancer

1 Mar 2022

Abstract excerpt

PURPOSE: The association of human leucocyte antigen (HLA) class I expression levels with the clinical course of many malignancies reflects their crucial role in the recognition and elimination of malignant cells by cognate T cells and NK cells. In colorectal cancer, results regarding this association are conflicting. The potential pathogenetic and therapeutic implications of this association prompted us to...

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PMID: 35277460
DOI: 10.1136/jitc-2021-004115

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