Article
Genetic heterogeneity in Chinese children with systemic lupus erythematosus
5 Feb 2021
Abstract excerpt
OBJECTIVES: Systemic lupus erythematosus (SLE) is a prototype autoimmune disease with extreme clinical heterogeneity and significant differences between populations. Here, we performed whole exome sequencing (WES) in 52 children with SLE from China. METHODS: The patients all fulfilled the 2012 SLICC criteria for the classification of SLE. Patients were enrolled if they met one of the following criteria: 1. age of...
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