Article
The frequency and differential pleiotropy of phenotypic nonspecificity in Drosophila melanogaster.
Genetics - 26 May 2023
Percival-Smith Anthony, Cheng Sheng, Ouellette Kassie
Abstract excerpt
The regulation of the initiation of transcription by transcription factors is often assumed to be dependent on specific recognition of DNA-binding sites and nonredundant. However, the redundant induction or rescue of a phenotype by transcription factors, phenotypic nonspecificity, challenges these assumptions. To assess the frequency of phenotypic nonspecificity in the rescue of transcription factor phenotypes,...
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