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Article

A male-specific effect of dominant-negative Fos.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Nov 2008

Pierre Wooly, Morra Rosa, Lucchesi John, Yedvobnick Barry

Abstract excerpt

The transcription factor Fos contains a basic DNA binding domain combined with a leucine zipper (bZip). Expression of a truncated form of Fos in Drosophila that contains only the bZip region (Fos bZip) elicits phenotypes resembling fos mutations. These effects presumably derive from competition between wild-type and truncated forms for dimerization partners, with the truncation acting in a dominant-negative...

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PMID: 18924113
DOI: 10.1002/dvdy.21751

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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