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Article

Reconstructing Clonal Evolution-A Systematic Evaluation of Current Bioinformatics Approaches.

International journal of environmental research and public health - 14 Mar 2023

Sandmann Sarah, Richter Silja, Jiang Xiaoyi, Varghese Julian

Abstract excerpt

The accurate reconstruction of clonal evolution, including the identification of newly developing, highly aggressive subclones, is essential for the application of precision medicine in cancer treatment. Reconstruction, aiming for correct variant clustering and clonal evolution tree reconstruction, is commonly performed by tedious manual work. While there is a plethora of tools to automatically generate...

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Identifiers

PMID: 36982036
DOI: 10.3390/ijerph20065128
PMCID: PMC10049679

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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