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Article

Association of DNA Promoter Methylation and BRAF Mutation in Thyroid Cancer.

Current oncology (Toronto, Ont.) - 2 Mar 2023

Jasmine Farzana, Aschebrook-Kilfoy Briseis, Rahman Mohammad M, Zaagman Garrett, Grogan Raymon H, Kamal Mohammed, Ahsan Habibul, Kibriya Muhammad G

Abstract excerpt

The BRAF V600E mutation and DNA promoter methylation play important roles in the pathogenesis of thyroid cancer (TC). However, the association of these genetic and epigenetic alterations is not clear. In this study, using paired tumor and surrounding normal tissue from the same patients, on a genome-wide scale we tried to identify (a) any association between BRAF mutation and DNA promoter methylation, and (b) if...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Identifiers

PMID: 36975440
DOI: 10.3390/curroncol30030227
PMCID: PMC10047424

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