Article
Classification of Thyroid Tumors Based on DNA Methylation Patterns.
Thyroid : official journal of the American Thyroid Association - 1 Sept 2023
Marczyk Vicente Rodrigues, Recamonde-Mendoza Mariana, Maia Ana Luiza, Goemann Iuri Martin
Abstract excerpt
Background: Alterations in DNA methylation are stable epigenetic events that can serve as clinical biomarkers. The aim of this study was to analyze methylation patterns among various follicular cell-derived thyroid neoplasms to identify disease subtypes and help understand and classify thyroid tumors. Methods: We employed an unsupervised machine learning method for class discovery to search for distinct...
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