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Article

Genome-wide methylation patterns in papillary thyroid cancer are distinct based on histological subtype and tumor genotype.

The Journal of clinical endocrinology and metabolism - 1 Feb 2014

Ellis Ryan J, Wang Yonghong, Stevenson Holly S, Boufraqech Myriem, Patel Dhaval, Nilubol Naris, Davis Sean, Edelman Daniel C, Merino Maria J, He Mei, Zhang Lisa, Meltzer Paul S, Kebebew Electron

Abstract excerpt

CONTEXT: Aberrant DNA methylation is known to be a major factor in oncogenesis and cancer progression, but effects of methylation in papillary thyroid cancer (PTC) are not well defined. OBJECTIVE: The objective of the study was to identify altered methylation patterns, which may be associated with PTC disease behavior. DESIGN: This study was a genome-wide methylation analysis of PTC. SETTING: The study was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Papillary

Share to DNA Methylation

Share to Genome, Human

Share to Proto-Oncogene Proteins B-raf

Share to Proto-Oncogene Proteins c-ret

Share to Thyroid Neoplasms

Source

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Identifiers

PMID: 24423287
DOI: 10.1210/jc.2013-2749
PMCID: PMC3913809

Genes

BRAF
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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