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Article

The relationship between RASSF1A promoter methylation and thyroid carcinoma: A meta-analysis of 14 articles and a bioinformatics of 2 databases (PRISMA).

Medicine - 1 Nov 2017

Niu Heng, Yang Jingyu, Yang Kunxian, Huang Yingze

Abstract excerpt

BACKGROUND: DNA promoter methylation can suppresses gene expression and shows an important role in the biological functions of Ras association domain family 1A (RASSF1A). Many studies have performed to elucidate the role of RASSF1A promoter methylation in thyroid carcinoma, while the results were conflicting and heterogeneous. Here, we analyzed the data of databases to determine the relationship between RASSF1A...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Gene Expression Regulation, Neoplastic

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Share to Promoter Regions, Genetic

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Share to Tumor Suppressor Proteins

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Identifiers

PMID: 29145283
DOI: 10.1097/MD.0000000000008630
PMCID: PMC5704828

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