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DNA Methylation Dynamics and Prognostic Implications in Metastatic Differentiated Thyroid Cancer

6 Mar 2025

Abstract excerpt

Background:Distant metastases (DM) are the leading cause of thyroid cancer-related death in patients with differentiated thyroid cancer (DTC). Despite significant progress in understanding DNA methylation in DTC, the methylation landscape of metastatic primary tumors and DM remains unclear. Our primary objective was to investigate DNA methylation dynamics during DTC progression, with a secondary goal of assessing...

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PMID: 40045915
DOI: 10.1089/thy.2024.0303

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