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Article

Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure.

European heart journal - 20 Jun 2023

Siedlinski Mateusz, Carnevale Lorenzo, Xu Xiaoguang, Carnevale Daniela, Evangelou Evangelos, Caulfield Mark J, Maffia Pasquale, Wardlaw Joanna, Samani Nilesh J, Tomaszewski Maciej, Lembo Giuseppe, Holmes Michael V, Guzik Tomasz J

Abstract excerpt

BACKGROUND AND AIMS: Observational studies have linked elevated blood pressure (BP) to impaired cognitive function. However, the functional and structural changes in the brain that mediate the relationship between BP elevation and cognitive impairment remain unknown. Using observational and genetic data from large consortia, this study aimed to identify brain structures potentially associated with BP values and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36972688
DOI: 10.1093/eurheartj/ehad101
PMCID: PMC10281555

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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