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CYP2D6 genetic polymorphisms in Saudi systemic lupus erythematosus patients: A cross-sectional study.

Saudi medical journal - 1 Mar 2023

Hassen Lena M, Daghestani Maha H, Omair Mohammed A, Althomali Arwa K, Almukaynizi Fatimah B, Almaghlouth Ibrahim A

Abstract excerpt

OBJECTIVES: To determine the prevalence of selected single nucleotide polymorphisms (rs1080985, rs28624811, rs1065852, rs28371725, and rs1135840) in cytochrome P450 2D6 (CYP2D6) gene among Saudi systemic lupus erythematosus (SLE) patients and to investigate the association between the genetic variants and clinical features of SLE. METHODS: This cross-sectional study was carried out on adult Saudi patients at King...

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Topics

Adult
Humans
Case-Control Studies
Cross-Sectional Studies
Cytochrome P-450 CYP2D6
Gene Frequency
Genetic Predisposition to Disease
Genotype
Lupus Erythematosus, Systemic
Polymorphism, Single Nucleotide
Saudi Arabia

Source

Open in PubMed Open full text

Identifiers

PMID: 36940959
DOI: 10.15537/smj.2023.44.3.20220581
PMCID: PMC10043891

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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