Article
CYP2D6 polymorphism in systemic lupus erythematosus patients.
European journal of clinical pharmacology - 1 Mar 1999
Kortunay S, Bozkurt A, Bathum L, Basci N E, Calgüneri M, Brøsen K, Kayaalp S O
Abstract excerpt
OBJECTIVES: To determine whether patients with idiopathic systemic lupus erythematosus (SLE) are associated with impaired CYP2D6 activity and to gain insight into whether there is an association between particular CYP2D6 genotypes and susceptibility to SLE, and whether CYP2D6 polymorphism is linked to any specific clinical features of SLE. METHODS: Debrisoquine sulfate (10 mg p.o.) was given to 159 healthy...
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