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Article

Significance of genetic polymorphism of CYP2D6 in the pathogenesis of systemic sclerosis.

Pharmacological reports : PR - 1 Jan 2012

Barańska Małgorzata, Dziankowska-Bartkowiak Bożena, Waszczykowska Elżbieta, Rychlik-Sych Mariola, Skrętkowicz Jadwiga

Abstract excerpt

BACKGROUND: Systemic sclerosis (SSc) belongs to the group of systemic diseases of the connective tissue, which are characterized by a chronic autoimmune inflammatory process. The studies on etiopathogenesis of autoimmune diseases focus on the impact the genetically conditioned impairment of xenobiotic metabolism may exert. The genetically polymorphic CYP2D6 is one of the most important phase I drug metabolizing...

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Share to Cytochrome P-450 CYP2D6
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

Share to Scleroderma, Systemic

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PMID: 22661184
DOI: 10.1016/s1734-1140(12)70773-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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