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Crosstalk between cGAS-STING pathway and autophagy in cancer immunity

1 Mar 2023

Abstract excerpt

The cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway is critical in cancer immunity. Autophagy is a highly conserved process that is responsible for the degradation of cytoplasmic material and is involved in both innate and adaptive immunity. Recently, cGAS-STING and autophagy have been shown to be interconnected, which may influence the progression of cancer. Although cGAS-STING and...

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Autophagy in Disease and Therapy
Inflammasome and immune disorders
interferon and immune responses

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36936940
DOI: 10.3389/fimmu.2023.1139595

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