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Antimicrobial resistance in Mycobacterium tuberculosis: mechanistic and evolutionary perspectives

16 Mar 2017

Abstract excerpt

Antibiotic-resistant Mycobacterium tuberculosis strains are threatening progress in containing the global tuberculosis epidemic. Mycobacterium tuberculosis is intrinsically resistant to many antibiotics, limiting the number of compounds available for treatment. This intrinsic resistance is due to a number of mechanisms including a thick, waxy, hydrophobic cell envelope and the presence of drug degrading and...

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PMID: 28369307
DOI: 10.1093/femsre/fux011

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