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Article

Lack of bidirectional association between age-related macular degeneration and Alzheimer's disease: A Mendelian randomization study.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Dec 2022

Jiang Li, Li Jin-Chen, Tang Bei-Sha, Guo Ji-Feng, Shen Lu

Abstract excerpt

INTRODUCTION: Observational studies have reported inconsistent results on the relationship between age-related macular degeneration (AMD) and Alzheimer's disease (AD). Therefore, we aimed to determine whether there is a causal association between AMD and AD. METHODS: This two-sample bidirectional Mendelian randomization (MR) study evaluated causal associations between advanced AMD and AD using summary data from...

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PMID: 36016508
DOI: 10.1002/alz.12775

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