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[Association between type 2 diabetes mellitus and the risk of developing cataracts: based on the research of two-sample Mendelian randomization].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology - 11 Dec 2024

Jiang X H, Zhang B, Chen W F, Zhao Y E

Abstract excerpt

Objective: To determine the causal relationship between cataracts and type 2 diabetes mellitus (T2D) by the Mendelian randomization (MR) analysis using the genome-wide association study (GWAS) data. Methods: Data on T2D and cataracts in the European population were obtained from the OpenGWAS database. The single nucleotide polymorphisms (SNPs) that met the genome-wide significance criteria (P<5×10⁻⁸) of T2D (48...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39648027
DOI: 10.3760/cma.j.cn112142-20240107-00005

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