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Article

Causal effects of genetically predicted testosterone on Alzheimer's disease: a two-sample mendelian randomization study.

Acta neurologica Belgica - 1 Apr 2024

Xu Qian, Shen Hong, Zhu Yifan, Zhang Junlei, Shen Zhongmei, Jiang Jianming, Zhou Jie

Abstract excerpt

OBJECTIVE: Although several studies have reported that testosterone may protect against Alzheimer's disease, no evidence of a causal relationship has been demonstrated. METHODS: A Mendelian randomization (MR) study was performed to determine the causal role of testosterone in Alzheimer's disease. The study utilized public databases obtained from separately published genome-wide associationstudies (GWAS)....

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PMID: 38007406
DOI: 10.1007/s13760-023-02426-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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