Article
Association of Behavioral and Clinical Risk Factors With Cataract: A Two-Sample Mendelian Randomization Study.
Investigative ophthalmology & visual science - 3 Jul 2023
Jiang Chen, Melles Ronald B, Sangani Poorab, Hoffmann Thomas J, Hysi Pirro G, Glymour M Maria, Jorgenson Eric, Lachke Salil A, Choquet Hélène
Abstract excerpt
Purpose: To investigate the association of genetically determined primary open-angle glaucoma (POAG), myopic refractive error (RE), type 2 diabetes (T2D), blood pressure (BP), body mass index (BMI), cigarette smoking, and alcohol consumption with the risk of age-related cataract. Methods: To assess potential causal effects of clinical or behavioral factors on cataract risk, we conducted two-sample Mendelian...
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