Article
Prognostic value of cell-free DNA in cerebrospinal fluid from lung cancer patients with brain metastases during radiotherapy.
Radiation oncology (London, England) - 11 Mar 2023
Qiao Simiao, Hao Yuying, Cai Linbo, Duan Xiaotong, Wang Lijuan, Zhou Aidong, Zhu Xiaoxia
Abstract excerpt
BACKGROUND: During the last decades, radiotherapy (RT) for non-small cell lung cancer (NSCLC) with brain metastases (BM) has been developed. However, the lack of predictive biomarkers for therapeutic responses has limited the precision treatment in NSCLC-BM. PATIENTS AND METHODS: In order to find the predictive biomarkers for RT, we investigated the influence of RT on the cell-free DNA (cfDNA) from cerebrospinal...
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