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Article

Fit-Seq2.0: An Improved Software for High-Throughput Fitness Measurements Using Pooled Competition Assays.

Journal of molecular evolution - 1 Jun 2023

Li Fangfei, Tarkington Jason, Sherlock Gavin

Abstract excerpt

The fitness of a genotype is defined as its lifetime reproductive success, with fitness itself being a composite trait likely dependent on many underlying phenotypes. Measuring fitness is important for understanding how alteration of different cellular components affects a cell's ability to reproduce. Here, we describe an improved approach, implemented in Python, for estimating fitness in high throughput via...

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Identifiers

PMID: 36877292
DOI: 10.1007/s00239-023-10098-0
PMCID: PMC10276102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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