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Article

A novel multiplex cell viability assay for high-throughput RNAi screening.

PloS one - 1 Jan 2011

Gilbert Daniel F, Erdmann Gerrit, Zhang Xian, Fritzsche Anja, Demir Kubilay, Jaedicke Andreas, Muehlenberg Katja, Wanker Erich E, Boutros Michael

Abstract excerpt

Cell-based high-throughput RNAi screening has become a powerful research tool in addressing a variety of biological questions. In RNAi screening, one of the most commonly applied assay system is measuring the fitness of cells that is usually quantified using fluorescence, luminescence and absorption-based readouts. These methods, typically implemented and scaled to large-scale screening format, however often only...

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PMID: 22162763
DOI: 10.1371/journal.pone.0028338
PMCID: PMC3230607

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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