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Article

High-Throughput, High-Precision Colony Phenotyping with Pyphe.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2022

Kamrad Stephan, Bähler Jürg, Ralser Markus

Abstract excerpt

Colony fitness screens are powerful approaches for functional genomics and genetics. This protocol describes experimental and computational procedures for assaying the fitness of thousands of microbial strains in numerous conditions in parallel. Data analysis is based on pyphe, an all-in-one bioinformatics toolbox for scanning, image analysis, data normalization, and interpretation. We describe a standard...

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PMID: 35524128
DOI: 10.1007/978-1-0716-2257-5_21

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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