Article
Comprehensive analysis of the impact of SNPs and CNVs on human microRNAs and their regulatory genes.
RNA biology - 1 Jan 2000
Duan Shiwei, Mi Shuangli, Zhang Wei, Dolan M Eileen
Abstract excerpt
Human microRNAs (miRNAs) are potent regulators of gene expression and thus involved in a broad range of biological processes. The objective of this study was to update the properties of human miRNAs and to search for SNPs and CNVs with potential effects on them. Based on the miRBase 13.0 database, we identified 380 (53.9%) precursor miRNAs (pre-miRNAs) embedded in gene loci that are enriched in biological...
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