Article
Association of Frequent Aspirin Use With Ovarian Cancer Risk According to Genetic Susceptibility.
JAMA network open - 1 Feb 2023
Hurwitz Lauren M, Webb Penelope M, Jordan Susan J, Doherty Jennifer A, Harris Holly R, Goodman Marc T, Shvetsov Yurii B, Modugno Francesmary, Moysich Kirsten B, Schildkraut Joellen M, Berchuck Andrew, Anton-Culver Hoda, Ziogas Argyrios, Menon Usha, Ramus Susan J, Wu Anna H, Pearce Celeste Leigh, Wentzensen Nicolas, Tworoger Shelley S, Pharoah Paul D P, Trabert Britton
Abstract excerpt
Importance: Frequent aspirin use is associated with reduced ovarian cancer risk, but it is unknown whether genetic factors modify this association. Understanding effect modifiers is important given that any use of aspirin for ovarian cancer chemoprevention will likely need to focus on specific higher-risk subgroups. Objective: To evaluate whether the association between frequent aspirin use and ovarian cancer is...
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