Article
Impact of regular aspirin use on overall and cancer-specific survival in patients with colorectal cancer harboring a PIK3CA mutation.
Acta oncologica (Stockholm, Sweden) - 1 Apr 2015
Kothari Nishi, Kim Richard, Jorissen Robert N, Desai Jayesh, Tie Jeanne, Wong Hui-Li, Faragher Ian, Jones Ian, Day Fiona L, Li Shan, Sakthinandeswaren Anuratha, Palmieri Michelle, Lipton Lara, Schell Michael, Teer Jamie K, Shibata David, Yeatman Timothy, Sieber Oliver M, Gibbs Peter, Tran Ben
Abstract excerpt
BACKGROUND: Recent data have suggested that regular aspirin use improves overall and cancer-specific survival in the subset of colorectal cancer (CRC) patients harboring PIK3CA mutations. However, the number of PIK3CA-mutated CRC patients examined in these studies was modest. Our collaborative study aims to validate the association between regular aspirin use and survival in patients with PIK3CA-mutated CRC....
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