Article
High-dimensional analysis of human CD8(+) T cell phenotype, function, and antigen specificity.
Current topics in microbiology and immunology - 1 Jan 2014
Newell Evan W, Lin Wenyu
Abstract excerpt
Antigen-specific T cells are critical initiators and orchestrators of the adaptive immune response. Categorizing antigen-specific T cell subsets is not a simple task given the diversity of these cells and the large number of parameters that can be considered. Here, we focus on human CD8(+) T cells and discuss the utility of high-dimensional mass cytometric analysis techniques for the concurrent identification and...
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