Article
Identification of Human Antigen-Specific CD4+ Cells with Peptide-MHC Multimer Technologies.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Chow I-Ting, Kwok William W
Abstract excerpt
Peptide-major histocompatibility complex class II (pMHCII) multimers have emerged as a convenient and powerful tool for characterization of CD4 T cell immune responses in a large variety of human diseases. Peptide-MHCII multimers can rapidly identify peptide antigens recognized by CD4 T cells via high-throughput peptide screening procedures. The specificity and phenotype of antigen-specific CD4 T cells can be...
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