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Analysis of clinical and genomic profiles of therapy-related myeloid neoplasm in Korea.

Human genomics - 23 Feb 2023

Yun Jiwon, Song Hyojin, Kim Sung-Min, Kim Soonok, Kwon Seok Ryun, Lee Young Eun, Jeong Dajeong, Park Jae Hyeon, Kwon Sunghoon, Yun Hongseok, Lee Dong Soon

Abstract excerpt

BACKGROUND: Therapy-related myeloid neoplasm (T-MN) rarely occurs among cancer survivors, and was characterized by poor prognosis. T-MN has germline predisposition in a considerable proportion. Here, clinical characteristics and germline/somatic variant profiles in T-MN patients were investigated, and the findings were compared with those of previous studies. METHODS: A review of medical records, cytogenetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36814285
DOI: 10.1186/s40246-023-00458-8
PMCID: PMC9948421

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