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Article

Clonal hematopoiesis: the nonhereditary genetics of age-associated cardiovascular disease.

Current opinion in cardiology - 1 May 2023

Sano Soichi, Thel Mark C, Walsh Kenneth

Abstract excerpt

PURPOSE OF REVIEW: Somatic mutations, described as noninherited changes in DNA that arise and are passed on to descendant cells, are well known to cause cancers; however, it is increasingly appreciated that the propagation of somatic mutations within a tissue may have a role in causing nonneoplastic disorders and abnormalities in elderly individuals. The nonmalignant clonal expansion of somatic mutations in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36811645
DOI: 10.1097/HCO.0000000000001032
PMCID: PMC10079606

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