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Article

Genomic ALK alterations in primary and relapsed neuroblastoma

17 Feb 2023

Abstract excerpt

BACKGROUND: Genomic alterations of the anaplastic lymphoma kinase gene (ALK) occur recurrently in neuroblastoma, a pediatric malignancy of the sympathetic nervous system. However, information on their development over time has remained sparse. METHODS: ALK alterations were assessed in neuroblastomas at diagnosis and/or relapse from a total of 943 patients, covering all stages of disease. Longitudinal information...

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PMID: 36807339
DOI: 10.1038/s41416-023-02208-y

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