Article
Examination of runs of homozygosity in relation to height in an endogamous Namibian population.
American journal of biological anthropology - 1 Jan 2023
Swinford Natalie, Gallagher Brenna, Sheehama Jacob, Lin Meng, Prall Sean, Scelza Brooke, Henn Brenna M
Abstract excerpt
OBJECTIVES: Height is a complex, highly heritable polygenic trait subject to both genetic composition and environmental influences. Recent studies suggest that a large proportion of height heritability is determined by the cumulative effect of many low allele frequency variants across the genome. Previous research has also identified an inverse relationship between height and runs of homozygosity (ROH); however,...
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