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Article

Genomics of clonal evolution in a rare essential thrombocythemia with coexisting Type 2 CALR and MPL S204P mutations.

Platelets - 1 Dec 2023

Wang Jing, Fu Wenjing, Bao Wenqiang, Gong Wenyu, Xu Shiyun, Ling Chun, Jin Qichuan, Zhang Qiguo

Abstract excerpt

Essential thrombocythemia (ET) with double driver mutations is a rare disease. ET patients with both MPL and Type 1 CALR mutations have been reported. Here, we report the first case of an ET patient with both MPL S204P and Type 2 CALR mutations and a summary of our literature review findings. In the patient whose case is reported here, the disease progressed to an accelerated phase 3.5 months after diagnosis....

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Source

Identifiers

PMID: 36786035
DOI: 10.1080/09537104.2023.2176167

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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