Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical characteristics and whole exome sequencing in JAK2V617F- and CALR-unmutated essential thrombocythemia.

Hematology (Amsterdam, Netherlands) - 1 Dec 2026

Thammayot Siraphop, Thongkumkoon Patcharawadee, Klangjorhor Jeerawan, Panyasit Noppamas, Niprapan Piangrawee, Hantrakun Nonthakorn, Punnachet Teerachat, Piriyakhuntorn Pokpong, Rattanathammethee Thanawat, Hantrakool Sasinee, Tantiworawit Adisak, Norasetthada Lalita, Chai-Adisaksopha Chatree, Rattarittamrong Ekarat

Abstract excerpt

OBJECTIVES: The aim of this study was to characterize the clinical features and outcomes of patients with JAK2 V617F- and CALR-unmutated essential thrombocythemia (ET) and to identify potential driver mutations through whole-exome sequencing (WES). METHODS: This was a cross-sectional study including patients diagnosed with ET between 2007 and 2024. Clinical characteristics and outcomes were compared between...

Topics

Join the communities discussing this publication.

Aged
Calreticulin
Cross-Sectional Studies
Exome Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Thrombocythemia, Essential

Source

Identifiers

PMID: 41566670
DOI: 10.1080/16078454.2026.2616933

Genes

CALR
ASXL1
DNMT3A
JAK2
MPL
MSH6
RUNX1
SETBP1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical characteristics and whole exome sequencing in JAK2V617F- and CALR-unmutated essential thrombocythemia.PMID 41566670Read ↗

Hematological relevance of JAK2 V617F and calreticulin mutations in Tunisian patients with essential thrombocythemia.Semantic proximity Read ↗

One thousand patients with essential thrombocythemia: the Mayo Clinic experience.Semantic proximity Read ↗

Assessing the thrombotic risk of patients with essential thrombocythemia in the genomic era.Semantic proximity Read ↗

The Roles of Genetic and Epigenetic Abnormalities in Essential ThrombocythemiaSemantic proximity Read ↗

Comparative thrombotic risk associated with CALR1 , CALR2 , and JAK2 V617F mutations in essential thrombocythemiaSemantic proximity Read ↗

Detecting Multiple Driver Mutations in a Patient with Essential Thrombocythemia.Semantic proximity Read ↗

Microparticle phenotypes are associated with driver mutations and distinct thrombotic risks in essential thrombocythemiaSemantic proximity Read ↗

Mutational profiling in suspected triple-negative essential thrombocythaemia using targeted next-generation sequencing in a real-world cohort.Semantic proximity Read ↗

Analysis of CALR-mutated essential thrombocythemia as a distinct disease entity compared with JAK2 V617F-mutated and triple-negative patients.Semantic proximity Read ↗

[Comparison of Clinical Characteristics of JAK2, CALR and Tri-Negative Driving Mutant Type in Patients with Essential Thrombocythemia].Semantic proximity Read ↗

JAK2 V617F, MPL, and CALR mutations in essential thrombocythaemia and major thrombotic complications: a single-institute retrospective analysis.Semantic proximity Read ↗

Sailing in deceptive calm: Navigating the undercurrents of essential thrombocythaemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.