Microparticle phenotypes are associated with driver mutations and distinct thrombotic risks in essential thrombocythemia

Abstract excerpt

Essential thrombocythemia (ET) is a Philadelphia-negative myeloproliferative neoplasm with high platelet counts and an increased risk of thrombosis. Acquired somatic mutations delineate four ET subtypes: JAK2-V617F , CALR -mutated, MPL -mutated, and “Triple-Negative” (TN).[1][1] CALR mutations

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