Article
RNA protein kinase SNP at -226 C<T is a biomarker for the clearance of HCV among Egyptian patients.
Immunological investigations - 1 Apr 2019
Wahid Ahmed, Hamzawy Mustafa A, Khalifa Mohamad M A, Gad Gamal F M, Bekhit Amany, Abdelwahab Sayed F
Abstract excerpt
BACKGROUND: RNA-dependant protein kinase R (PKR) is a primary mediator in the defence mechanism of interferon against viral replication and pathogenesis during Hepatitis C virus (HCV) infection. In the present study, we have examined the role of Single Nucleotide Polymorphisms (SNPs) in the promoter region of PKR and the serum level of the same protein on the outcome of HCV-infected Egyptian patients. PATIENTS...
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