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Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development

21 Feb 2019

Abstract excerpt

The current understanding of mammalian kidney development is largely based on mouse models. Recent landmark studies revealed pervasive differences in renal embryogenesis between mouse and human. The scarcity of detailed gene expression data in humans therefore hampers a thorough understanding of human kidney development and the possible developmental origin of kidney diseases. In this paper, we present a...

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PMID: 30789893
DOI: 10.1371/journal.pbio.3000152

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