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Article

Potential prognostic role of somatic mutations in a set of cancer susceptibility genes in ovarian carcinoma: A follow-up multicentric study from Pakistan.

Cancer biomarkers : section A of Disease markers - 1 Jan 2023

Masood Atika, Sarfaraz Rahat, Zaki Saima, Shami Amira, Khaliq Saba, Naseem Nadia

Abstract excerpt

BACKGROUND: Genetic mutations, peritoneal metastasis and frequent development of chemoresistance worsen the prognosis of ovarian carcinoma. OBJECTIVE: The objective of the study is to determine mutations in cancer susceptibility genes in relation with chemotherapy response. METHODS: In this follow up descriptive study, 47 consenting female patients diagnosed with surface epithelial ovarian cancer were observed...

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Source

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Identifiers

PMID: 36776043
DOI: 10.3233/CBM-220267
PMCID: PMC12412808

Genes

BAP1
BRCA1
CHEK2
CTNNB1
PALB2
PIK3CA
BRCA2
HOXB13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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