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Frequency of germline mutations in BRCA1 and BRCA2 in ovarian cancer patients and their effect on treatment outcome

1 Jul 2019

Abstract excerpt

Aim of work: Reporting the incidence and the variants of BRCA1 /2 mutations in ovarian cancer patients exploring their effects on the treatment outcomes. Patients and methods: In total, 104 patients with epithelial ovarian cancer were prospectively recruited to the study. Analysis consisted of the sequencing of all the translated exons and immediately adjacent intronic regions of the BRCA1/2 genes. Responses to...

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PMID: 31372034
DOI: 10.2147/cmar.s206817

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